“Many cosmetic surgeons will tell you that if you keep your injections up, the muscle that makes you frown, or squint, will eventually “give up”. “The muscle does become more relaxed and perhaps weakened,” says Frank Vella, Cosmetic Physician. “But having Anti wrinkle injections is more of a behavioural modification – it retrains you not to use those muscles. If you have five, six, or more treatments, you may find that you are stretching out the normal time Anti wrinkle injections lasts of around four months. But you will still need top up treatments.”